AZD1080 Culture-TreatedAZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3? and GSK3? with Ki of 6. 9 nM and 31 nM, respectively, shows >14 fold selectivity against CDK2, CDK5, CDK1 and Erk2.
and Pim3 in cell-free assays
Sulfachloropyridazine is an antibiotic used to treat a variety of bacterial infections
Indigo dye is an organic compound with a distinctive blue color
inhibiting pyruvate transport across the plasma membrane of trypanosomes with Ki value of 49
Crenigacestat (LY3039478) is an oral Notch inhibitor with an IC50 of 0
Cytochrome P450 1A2
It increases plasma adrenocorticotropic hormone (ACTH) levels and potentiates serum thyrotrophin (TSH) levels by activating the central cholinergic system
Ginsenoside Rb1 is a protopanaxadiol that has diverse in vitro and in vivo effects
Sunitinib Malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFR
no inhibition to PKA/B/C
which considerably expands the MYA 4Y PLUS microbalance functionality
Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs)