Rabusertib (LY2603618) high temperature caps

Rabusertib (LY2603618) high temperature capsRabusertib (LY2603618) is a highly selective Chk1 inhibitor with potential anti tumor activity in a cell free assay. IC50=7 nM, showing approximately 100 fold more potent against Chk1 than against any of the other protein kinases evaluated.

used in the management of hypertension and congestive heart failure

but binds more weakly to Mcl-1 and A1

bipolar disorder and prevention of migraine headaches

Abiraterone is a potent CYP17 inhibitor with IC50 of 2 nM in a cell-free assay

Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor

Dip the end of the cylinder into sterile silicone grease before pressing to the bottom of a culture dish to create an isolated well

~10-fold selectivity versus JAK3

inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cells

2 IN/2 OUT

Aminocaproic acid is a derivative and analogue of the amino acid lysine

Specific applications include accurate and precise pipetting of expensive reagents

Corning 384 well Black Tissue Culture Treated Microplate