AZ5104 TC-TreatedAZ5104, the demethylated metabolite of AZD 9291, is a potent EGFR inhibitor with IC50 of <1 nM, 6 nM, 1 nM, and 25 nM for EGFR (L858R T790M), EGFR (L858R), EGFR (L861Q), and EGFR (wildtype), respectively. Phase 1.
colorless liquid hydrocarbon classified as a cyclic monoterpene
exhibits greater than 10
a phenylpropanoid glycoside from lemon verbena
which is found in the plants such as Cnidium monnieri
The ionizer activates when the balance door opens
which is a mixture of different quaternary ammonium salts
Kitasamycin is a macrolide antibiotic
inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays
a natural protoalkaloid in the extract of bitter orange and other citrus species
a penicillin antibiotic used to treat bacterial infections
Prasugrel hydrochloride is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome
The 12mm O