RAF709 Duty

RAF709 DutyRAF709 is a potent inhibitor of B C RAF kinase with almost equivalent IC50 values of 0. 4 nM for B RAF and C RAF, showing a high level of selectivity, demonstrating greater than 99% on target binding to BRAF, BRAFV600E, and CRAF at 1 ? M and very few off targets with DDR1 (>99%), DDR2 (86%), FRK (92%), and PDGFRb (96%), the only kinases with binding >80% at 1 ? M.

It also inhibits ROS1

14 rubber stopper

33mm HDPE cap with 18in Female Luer and Male Luer Lock Plug

Vilazodone HCl is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of 5-HT1A receptors

PD 128907 HCl is a potent and selective dopamine D3 receptor agonist

exhibiting no inhibitory activities against DNA topoisomerase II or ligase

L-Hisidine is an

Corning (This is the suggested replacement for 4961)Lambda Plus Pipettors have been engineered to provide the highest levels of accuracy

ACY-738 inhibits HDAC6 with low nanomolar potency (IC50=1

4 per case - COP

1395-32HTSC) with GL32 threads to allow for aseptic reagent delivery or culture sampling using a syringe and needle

inhibits 5-HT1A